Lol good luck but I wouldn’t recommend it as your daily os. Qubes is for those who have got a nation state on their back or something like that. For most people, default fedora is more than enough.

(see https://www.privacyguides.org/en/os/qubes-overview/ and https://www.privacyguides.org/en/desktop/)

Probably Qubes OS

You are supposed to use /var/home/user instead of /home/user in your paths, scripts, etc (or /var/$HOME). Im not certain on the why but iirc its because on immutable systems only /var is writable so anything writable has to be under it.

Centralization is not a good thing IMO. Im glad Fedora is bothering to maintain their own repo no matter how useless we find it.

Just search or ask whatever questions you have about Linux (just like your question on GPU use). Overtime you will gain extensive knowledge of linux and before you know it you will be a linux power user.

Yes but for apps like Signal or WhatsApp you probably want them running all the time (in the background) which is not practical with waydroid right now due to its high battery usage. Running one OS on top of another has its toll even its in a container and not a vm. But its okay for foreground apps.